Fraunhofer Institute for Microstructure of Materials and Systems IMWSProteins play a decisive role in determining the function of cells and tissues—not only through their sequence, but also through their structure, interactions, and post-translational modifications. Modern protein analytics provides access to this molecular level in both qualitative and quantitative terms, enabling detailed characterization of biological processes, material properties, and quality-related parameters.
At Fraunhofer IMWS, we possess in-depth technical expertise and state-of-the-art analytical technologies for the comprehensive characterization of proteins in complex samples. Our latest-generation Orbitrap Astral (Thermo Fisher Scientific) mass spectrometer (the first of its kind in the Fraunhofer Society) enables high-resolution analyses with high sample throughput.
We provide precise protein analyses from minimal sample quantities, even in challenging matrices such as the extracellular matrix (ECM). Our services include the untargeted identification and quantification of post-translational modifications (e.g., phosphorylation, degradation, and aging markers, AGEs), de novo sequencing of antibodies and unknown proteins, contamination analysis of protein preparations (e.g., host cell proteins), and the generation of protein profiles in animal and plant-based foods, including bioactive or flavor-influencing peptides.
